Prophylactic Use of Ondansetron for Hypotension Prevention in Cases Undergoing Cesarean Section Post-Spinal Anesthesia

Background: Ondansetron is being administrated to prevent post spinal hypotension and its affects are promising. Globally, researches conducted identify the prophylactic effects of ondansetron. Aim: To determine frequency maternal with or without intravenous administration ondansetron in cases undergoing cesarean section post-spinal anesthesia. Study design: Randomized controlled trial Place duration study: Jinnah Postgraduate Medical Centre, Karachi from 1st February 2017 August 2017. Methodology: Eighty four pregnant females between 18-35 years age enrolled for cesarean-section under anesthesia were included. Patients having a history cardiorespiratory renal disorders, as well bradycardia tachycardia, hypo/hypertension hyperglycemia excluded. The patients randomly divided into Group A (ondansetron) B (control) by using codes placed sealed, sequentially numbered envelopes. mean value arterial blood pressure heart rate was documented at 3 min interval 10 minutes then every 5 till 30 after Results: group 26.57±5.28 26.88±4.62 years. Thirty two (38.10%) ASA I 52 (61.90%) II. 39.36±1.65 weeks 39.79±1.47 weeks. Mean 138.44±13.59mmHg. Frequency seen 08 (19.05%) while 22 (52.38%) (p=0.001). Conclusion: There less Keywords: Spinal anesthesia, Hypotension, Ondansetrone